ea0035p426 | Diabetes complications | ECE2014
Vasilkova Volha
, Silin Arkadij
, Martinkov Victor
, Naumenko Elena
, Zekenova Kulash
, Mokhort Tatiana
Introduction: Diabetic nephropathy (DN) is one of the most serious chronic complications of diabetes mellitus characterized by persistent albuminuria, raised arterial blood pressure, a lowered glomerular filtration rate, and high-risk of cardiovascular morbidity and mortality. The vascular genes (Angiotensin-converting enzyme) ACE, and (aldosterone synthase) CYP11B2 are involved in alterations in vascular endothelium, and are suggested to play a role in the susceptibi...